P-CLASS

2025-05-15

Highthroughput molecular interaction analysis system P-CLASS


Based on Surface Plasmon Resonance (SPR) technology, the integrated micron-scale flow control system ensures ultra-high sensitivity of the instrument, which can comfortably cope with the high-throughput screening and characterization of all kinds of complex samples. The innovative intelligent software design, supporting 4-pin parallel or independent operation, together with rich and stable sensing chips, can perfectly assist life science research and biopharmaceutical development at every stage of the application, from the early mechanism of drug research, screening to the subsequent validation and quality control.



Insight into the ultimate of moleculespursuit

of the source of life

High throughput: Individual 4-needle, 8-channel microplate-based design


Flexible: free selection of injection needles, no need to fill the empty space


Easy to use: building blocks for experiments, easy to learn interface



High Precision Detection and Resolution of Biomolecular Interactions


P-CLASS is a surface plasmon resonance (SPR) system for label-free studies of biomolecular interactions. It provides high-quality, high-throughput analytical capabilities for a wide range of biological applications with exceptional reliability.



     Basic parameters



  • Detection principle
    Surface Plasmon Resonance, SPR
  • Data Information
    Kinetic and affinity data (ka, kd, KD), binding specificity and screening, ranking, competition, concentration quantification
  • Sample type
    Small molecules, proteins, nucleic acids, polysaccharides, lipids, cells, viruses, etc. and various complex samples or clinical samples
  • Refractive index range
    1.33 - 1.40
  • Flow rate
    1 - 100μL/min
  • Injection volume
    1 - 300μL
  • Number of injection needles/channel
    4 independent injection needles, 8 detection channels (flow cells)
  • Reagent loading
    Compatible with 2×96-well or 384-well standard and/or deep-well plates, as well as Eppendorf tubes
  • Analysis temperature
    4 - 40℃
  • Sample temperature control
    4 - 40℃
  • Data collection frequency
    1 or 10 Hz
  • How it works
    1) Automatic injection 2) Manual injection
  • Detection method
    1) Series detection 2) Parallel detection
  • Reference subtraction
    Double reference subtraction (blank and zero concentration)
  • Single cycle kinetics
    Support
  • Automatic correction of organic solvents
    Support
  • Sample recovery (fishing)
    Support
  • Epitope analysis
    Optional
  • Safety regulations
    21 CFR Part 11 & GxP (optional)
  • Specification
    650 × 600 × 550mm
  • Weight
    70 kg

      Detection range


  • Molecular weight detection limit
    No molecular weight limit for organic molecules
  • Baseline noise
    <0.03 RU (RMS)
  • Baseline drift (single subtraction reference channel)
    <0.03 RU/min
  • The binding rate constant (ka) scope
    103 - 3×109 M-1s-1
  • The dissociation rate constant (kd) scope
    10-6 - 0.5 s-1
  • Affinity range
    10-15 - 10-3 M（fM - mM)


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